Oxford involved in comprehensive study of the human genome
Sunday, February 24th, 2008A panoramic view of human genetic diversity has been achieved, scientists report in this week’s Nature. The international team, including Jennifer Schymick from Oxford’s Department of Physiology, Anatomy and Genetics has examined 29 populations, tracking over 500,000 markers in the human genome. It’s one of the most comprehensive studies of its kind and shows increased associations between genetic markers (increased linkage disequilibrium) the further away a population is from Africa. Their research gives additional evidence that a ‘migration bottleneck’ occured as early humans slowly made their way out of Africa and populated Europe before spreading to the rest of the world. It also demonstrates how useful studying the number of copies of a gene can be in population-genetic studies.